Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | JAK1 | P23458 | 3/20 | 0.38 |
| ▸ | JAK3 | P52333 | 3/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.35 |
| ▸ | CDK2 | P24941 | 3/20 | 0.35 |
| ▸ | CSF1R | P07333 | 3/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.33 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.33 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924096 | 0.84 | PIK3C3 (0.39) | PDE4APDE4BPDE4CPDE4DJAK2 | |
| SCHEMBL6919738 | 0.75 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DCCNE1 | |
| SCHEMBL6918526 | 0.71 | PGR (0.41) | JAK2JAK1JAK3PIK3C3TYK2 | |
| SCHEMBL6920616 | 0.71 | PGR (0.41) | JAK2JAK1JAK3PIK3C3TYK2 | |
| SCHEMBL6919141 | 0.69 | PGR (0.42) | PIK3C3YTHDF2YTHDF3YTHDF1 | |
| SCHEMBL6923987 | 0.68 | PIK3C3 (0.42) | JAK2JAK1JAK3PIK3C3CSF1R | |
| SCHEMBL6918752 | 0.66 | PIK3C3 (0.38) | JAK2JAK1JAK3PIK3C3CSF1R | |
| SCHEMBL19583314 | 0.65 | YTHDF2 (0.48) | JAK2JAK1JAK3PIK3C3CSF1R | |
| SCHEMBL28005753 | 0.65 | NPC1 (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28416982 | 0.63 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |