Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT7 | O95251 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827260 | 0.82 | NOTUM (0.38) | KAT7LMNACHRM1NR1I2KDM4B | |
| SCHEMBL6827158 | 0.79 | KDM4E (0.34) | LMNACHRM1NR1I2KDM4BTBXA2R | |
| SCHEMBL6827359 | 0.76 | PGR (0.38) | LMNACHRM1NR1I2KDM4BTBXA2R | |
| SCHEMBL6824827 | 0.76 | PGR (0.38) | LMNACHRM1NR1I2KDM4BTBXA2R | |
| SCHEMBL6827087 | 0.75 | PGR (0.39) | LMNAPDE2A | |
| SCHEMBL6923814 | 0.74 | NR1I2 (0.38) | LMNACHRM1NR1I2KDM4BTBXA2R | |
| SCHEMBL6924372 | 0.72 | LMNA (0.41) | KAT7LMNARAB9ACHRM1CHEK2 | |
| SCHEMBL6919738 | 0.72 | PDE4A (0.36) | LMNACHRM1NR1I2KDM4BTBXA2R | |
| SCHEMBL6919295 | 0.70 | NR1I2 (0.42) | LMNACHRM1NR1I2KDM4BTBXA2R | |
| SCHEMBL6827816 | 0.69 | HTT (0.43) | KDM4EALDH1A1ATMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | claimed |
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |