Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489674 | 0.83 | CA1 (0.46) | LMNAALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL18537139 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2NFE2L2LMNAALDH1A1KDM4E | |
| SCHEMBL17894183 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2NFE2L2LMNAALDH1A1KDM4E | |
| SCHEMBL17894153 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2NFE2L2LMNAALDH1A1KDM4E | |
| SCHEMBL31438691 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2NFE2L2LMNAALDH1A1KDM4E | |
| SCHEMBL8417921 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2NFE2L2LMNAALDH1A1KDM4E | |
| SCHEMBL11574544 | 0.74 | ALDH1A1 (0.41) | SMN1; SMN2NFE2L2ALDH1A1TP53MEN1 | |
| SCHEMBL20675 | 0.74 | CYP19A1 (0.45) | SMN1; SMN2NFE2L2LMNAALDH1A1KDM4E | |
| SCHEMBL10451316 | 0.73 | AR (0.49) | SMN1; SMN2NFE2L2ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL29749364 | 0.73 | AR (0.49) | SMN1; SMN2NFE2L2ALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214311-B1 | NOVEL INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2004-09-15 | — | — | EP | disclosed |
| US-6296785-B1 | OPHTHALMIC AND CONTACT LENSES; WINDOWS, SAFETY GLASS FOR CARS | PPG INDUSTRIES OHIO, INC. | 2001-10-02 | — | — | US | disclosed |