SCHEMBL7489674

SCHEMBL7489674

C#CC(O)(c1ccccc1OC)c1ccccc1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
CA12 O43570 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA4 P22748 1/20 0.46
GAA P10253 3/20 0.44
TP53 P04637 2/20 0.43
TSHR P16473 1/20 0.43
ALDH1A1 P00352 4/20 0.42
CASR P41180 1/20 0.42
ENPP2 Q13822 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ORAI1 Q96D31 1/20 0.39
ORAI2 Q96SN7 1/20 0.39
ORAI3 Q9BRQ5 1/20 0.39
ADRA2B P18089 1/20 0.39
PTGS1 P23219 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11574544 0.89 ALDH1A1 (0.41) CA1CA2CA7CA9CA12
SCHEMBL8102819 0.87 CYP1A2 (0.43) CA1CA2CA7CA9CA12
SCHEMBL30057200 0.85 MAPT (0.44) CA1CA2CA7CA9CA12
SCHEMBL7552122 0.84 NFE2L2 (0.43) CA1CA2CA7CA9CA12
SCHEMBL6919880 0.83 SMN1; SMN2 (0.40) CA1CA2CA7CA9CA12
SCHEMBL31708116 0.82 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL8784494 0.79 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL7530417 0.78 CA12 (0.47) CA1CA2CA7CA9CA12
SCHEMBL9258680 0.78 RAB9A (0.41) GAATP53TSHRALDH1A1MEN1
SCHEMBL9326049 0.77 CASR (0.57) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10159966-B2 Catalyst complexes with carbene ligand and method for making same and use in metathesis reaction GUANG MING INNOVATION COMPANY (WUHAN) (CN) 2018-12-25 US disclosed
US-20150367338-A1 CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION GUANG MING INNOVATION COMPANY (WUHAN) (CN) 2015-12-24 US disclosed
US-20150367338-A1 CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION GUANG MING INNOVATION COMPANY (WUHAN) (CN) 2015-12-24 US disclosed
US-20150367338-A1 CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION GUANG MING INNOVATION COMPANY (WUHAN) (CN) 2015-12-24 US disclosed
EP-2943499-A1 CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION Guangming Innovation Company (Wuhan) (CN) 2015-11-18 EP disclosed
WO-2014108071-A1 CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION GUANG MING INNOVATION COMPANY (WUHAN) (CN) 2014-07-17 WO disclosed
WO-2014108071-A1 CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION GUANG MING INNOVATION COMPANY (WUHAN) (CN) 2014-07-17 WO disclosed
EP-0946536-B1 (BENZOFURAN)NAPHTHOPYRANS, THE COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM CORNING INC (US) 2002-02-27 EP disclosed
EP-0946536-A4 (BENZOFURAN)NAPHTHOPYRANS, THE COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM CORNING INC (US) 2000-03-08 EP disclosed
US-6018059-A INTERESTING PHOTOCHROMIC PROPERTIES; CAN BE CROSSLINKED OR POLYMERIZED WHEN FUNCTIONALIZED WITH EPOXY, ALKENYL, OR (METH)ACRYLOYL GROUPS; OPHTHALMIC DEVICES, GLAZINGS, OR SOLAR ARTICLES CORNING INCORPORATED (US) 2000-01-25 US disclosed
EP-0946536-A1 (BENZOFURAN)NAPHTHOPYRANS, THE COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM CORNING INCORPORATED (US) 1999-10-06 EP disclosed
WO-1998028289-A1 (BENZOFURAN)NAPHTHOPYRANS, THE COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM CORNING INCORPORATED (US) 1998-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10159966-B2 Catalyst complexes with carbene ligand and method for making same and use in metathesis reaction MSMO1, ALOX12, SQLE CA1 2451/4885CA2 2337/4885CA7 2345/4885
US-20150367338-A1 CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION MSMO1, ALOX12, SQLE CA1 2451/4885CA2 2337/4885CA7 2345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.