Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17894183 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2NFE2L2ALDH1A1TP53MAPT | |
| SCHEMBL8729134 | 0.81 | NFE2L2 (0.41) | SMN1; SMN2NFE2L2ALDH1A1TP53HPGD | |
| SCHEMBL18537139 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2NFE2L2ALDH1A1TP53MAPT | |
| SCHEMBL20675 | 0.77 | CYP19A1 (0.45) | SMN1; SMN2NFE2L2ALDH1A1TP53MAPT | |
| SCHEMBL6919880 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2NFE2L2ALDH1A1TP53MAPT | |
| SCHEMBL31438691 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2NFE2L2ALDH1A1TP53MAPT | |
| SCHEMBL8417921 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2NFE2L2ALDH1A1TP53MAPT | |
| SCHEMBL18550496 | 0.75 | NFE2L2 (0.41) | SMN1; SMN2NFE2L2ALDH1A1TP53MEN1 | |
| SCHEMBL28799825 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2NFE2L2ALDH1A1MAPTLMNA | |
| Lithium SCHEMBL29714938 | 0.74 | ALDH1A1 (0.38) | SMN1; SMN2NFE2L2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12114660-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2024-10-15 | — | — | US | disclosed |
| US-20230371516-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2023-11-23 | — | — | US | disclosed |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-20220159962-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2022-05-26 | — | — | US | disclosed |
| US-11284620-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2022-03-29 | — | — | US | disclosed |
| EP-3808181-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | Dow AgroSciences LLC (US) | 2021-04-21 | — | — | EP | disclosed |
| EP-3808181-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | Dow AgroSciences LLC (US) | 2021-04-21 | — | — | EP | disclosed |
| EP-3240773-B9 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2021-01-13 | — | — | EP | disclosed |
| EP-3240773-B9 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2021-01-13 | — | — | EP | disclosed |
| EP-3240424-B1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-09-16 | — | — | EP | disclosed |
| US-20200120936-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2020-04-23 | — | — | US | disclosed |
| US-10595531-B2 | Use of picolinamide compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2020-03-24 | — | — | US | disclosed |
| US-10588318-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2020-03-17 | — | — | US | disclosed |
| US-10182568-B2 | Use of picolinamide compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-22 | — | — | US | disclosed |
| EP-3240773-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow AgroSciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-3240424-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | Dow AgroSciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2017-10-19 | — | — | US | disclosed |
| US-20170290333-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2017-10-12 | — | — | US | disclosed |
| WO-2016122802-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-08-04 | — | — | WO | disclosed |
| WO-2016109257-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10595531-B2 | Use of picolinamide compounds as fungicides | PFAS, FKBP2, FKBP14 | SMN1; SMN2 2238/4885NFE2L2 3504/4885ALDH1A1 1160/4885 |
| US-20170290333-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | SMN1; SMN2 2463/4885NFE2L2 3101/4885ALDH1A1 1350/4885 |
| US-10182568-B2 | Use of picolinamide compounds as fungicides | PFAS, FKBP2, FKBP14 | SMN1; SMN2 2238/4885NFE2L2 3504/4885ALDH1A1 1160/4885 |
| US-20220159962-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | SMN1; SMN2 2463/4885NFE2L2 3101/4885ALDH1A1 1350/4885 |
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | PFAS, FKBP2, FKBP14 | SMN1; SMN2 2238/4885NFE2L2 3504/4885ALDH1A1 1160/4885 |
| US-20200120936-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | SMN1; SMN2 2463/4885NFE2L2 3101/4885ALDH1A1 1350/4885 |
| US-20230371516-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | SMN1; SMN2 2463/4885NFE2L2 3101/4885ALDH1A1 1350/4885 |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | SMN1; SMN2 2463/4885NFE2L2 3101/4885ALDH1A1 1350/4885 |
| US-12114660-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | SMN1; SMN2 2463/4885NFE2L2 3101/4885ALDH1A1 1350/4885 |
| US-11284620-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | SMN1; SMN2 2463/4885NFE2L2 3101/4885ALDH1A1 1350/4885 |
| US-10588318-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | SMN1; SMN2 2463/4885NFE2L2 3101/4885ALDH1A1 1350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.