Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713714 | 0.93 | KDR (0.43) | KDRGRIK1KDM4EMAPK1TP53 | |
| SCHEMBL6708830 | 0.91 | GRIK1 (0.40) | GRIK1TP53TDP1POLBRXFP1 | |
| SCHEMBL6709991 | 0.86 | KDR (0.44) | KDRGRIK1KDM4EMAPK1TP53 | |
| SCHEMBL6713876 | 0.85 | GRIK1 (0.42) | GRIK1TP53POLBRXFP1MAPT | |
| SCHEMBL6708679 | 0.85 | GRIK1 (0.44) | GRIK1TP53TDP1POLBRXFP1 | |
| SCHEMBL6713760 | 0.83 | GRIK1 (0.42) | GRIK1TP53TDP1RXFP1MAPT | |
| SCHEMBL6714034 | 0.82 | KMT2A (0.47) | KDRGRIK1KDM4EMAPK1TP53 | |
| SCHEMBL6709929 | 0.82 | GRIK1 (0.49) | KDRGRIK1TDP1MAPTGAA | |
| SCHEMBL6712044 | 0.81 | GPR35 (0.46) | GRIK1TP53POLBRXFP1MAPT | |
| SCHEMBL6713931 | 0.81 | GRIK1 (0.41) | GRIK1TDP1RXFP1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |