Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920531 | 0.86 | NPSR1 (0.41) | GPR35HIF1ANPSR1RXFP1ALDH1A1 | |
| SCHEMBL6711741 | 0.84 | HIF1A (0.47) | GPR35HIF1ANPSR1RXFP1MEN1 | |
| SCHEMBL6707938 | 0.83 | ALDH1A1 (0.33) | L3MBTL1PARP14ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6712466 | 0.82 | GPR35 (0.39) | GPR35HIF1ANPSR1RXFP1ALDH1A1 | |
| SCHEMBL6710114 | 0.82 | KMT2A (0.42) | L3MBTL1GPR35NPSR1RXFP1ALDH1A1 | |
| SCHEMBL6710320 | 0.81 | PARP14 (0.39) | GPR35HIF1ANPSR1RXFP1PARP14 | |
| SCHEMBL6711411 | 0.81 | GPR35 (0.42) | GPR35HIF1ANPSR1RXFP1MAPT | |
| SCHEMBL6712050 | 0.81 | GPR35 (0.35) | GPR35 | |
| SCHEMBL6713465 | 0.81 | GPR35 (0.43) | GPR35HIF1ANPSR1RXFP1 | |
| SCHEMBL6713366 | 0.81 | ADORA3 (0.39) | GPR35HIF1ANPSR1RXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |