Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.41 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.41 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.41 |
| ▸ | ADH5 | P11766 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918526 | 1.00 | PGR (0.41) | PGRYTHDF3YTHDF1YTHDF2ADH5 | |
| SCHEMBL6919141 | 0.99 | PGR (0.42) | PGRYTHDF3YTHDF1YTHDF2ADH5 | |
| SCHEMBL6924518 | 0.88 | PGR (0.36) | PGRYTHDF3YTHDF1YTHDF2ADH5 | |
| SCHEMBL6918752 | 0.76 | PIK3C3 (0.38) | YTHDF3YTHDF1YTHDF2PIK3C3JAK2 | |
| SCHEMBL6923987 | 0.75 | PIK3C3 (0.42) | YTHDF3YTHDF1YTHDF2PIK3C3JAK2 | |
| SCHEMBL6924096 | 0.74 | PIK3C3 (0.39) | YTHDF3YTHDF1YTHDF2PDE3BPDE3A | |
| SCHEMBL6827915 | 0.73 | CYP11B1 (0.41) | PGRADH5CYP11B1CYP11B2HTR2A | |
| SCHEMBL6827356 | 0.73 | CD38 (0.37) | PGRADH5MTORJAK2JAK1 | |
| SCHEMBL6827359 | 0.72 | PGR (0.38) | PGRADH5CYP11B1CYP11B2HTR2A | |
| SCHEMBL6824827 | 0.72 | PGR (0.38) | PGRADH5CYP11B1CYP11B2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |