Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.37 |
| ▸ | JAK1 | P23458 | 3/20 | 0.37 |
| ▸ | TYK2 | P29597 | 3/20 | 0.37 |
| ▸ | JAK3 | P52333 | 3/20 | 0.37 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.37 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.37 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918526 | 0.76 | PGR (0.41) | PIK3C3JAK2JAK1TYK2JAK3 | |
| SCHEMBL6920616 | 0.76 | PGR (0.41) | PIK3C3JAK2JAK1TYK2JAK3 | |
| SCHEMBL6919141 | 0.74 | PGR (0.42) | PIK3C3YTHDF3YTHDF1YTHDF2 | |
| SCHEMBL6827158 | 0.72 | KDM4E (0.34) | KDM4EALDH1A1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL6924096 | 0.68 | PIK3C3 (0.39) | PIK3C3JAK2JAK1TYK2JAK3 | |
| SCHEMBL6923987 | 0.67 | PIK3C3 (0.42) | PIK3C3JAK2JAK1TYK2JAK3 | |
| SCHEMBL19583314 | 0.66 | YTHDF2 (0.48) | PIK3C3JAK2JAK1TYK2JAK3 | |
| SCHEMBL6924518 | 0.66 | PGR (0.36) | PIK3C3YTHDF3YTHDF1YTHDF2 | |
| SCHEMBL6925607 | 0.66 | PDE4A (0.39) | PIK3C3JAK2JAK1TYK2JAK3 | |
| SCHEMBL12612092 | 0.66 | YTHDF2 (0.81) | JAK2JAK1TYK2JAK3YTHDF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |