Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.42 |
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.36 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.36 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 4/20 | 0.35 |
| ▸ | JAK1 | P23458 | 4/20 | 0.35 |
| ▸ | JAK3 | P52333 | 4/20 | 0.35 |
| ▸ | TYK2 | P29597 | 3/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | ARF6 | P62330 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19583314 | 0.75 | YTHDF2 (0.48) | PIK3C3YTHDF2YTHDF3YTHDF1JAK2 | |
| SCHEMBL6918526 | 0.75 | PGR (0.41) | PIK3C3YTHDF2YTHDF3YTHDF1JAK2 | |
| SCHEMBL6920616 | 0.75 | PGR (0.41) | PIK3C3YTHDF2YTHDF3YTHDF1JAK2 | |
| SCHEMBL6919141 | 0.73 | PGR (0.42) | PIK3C3YTHDF2YTHDF3YTHDF1 | |
| SCHEMBL6823849 | 0.73 | NR1I2 (0.42) | NR1I2KDM4BCHRM1TBXA2RADRA1A | |
| SCHEMBL6924096 | 0.73 | PIK3C3 (0.39) | PIK3C3YTHDF2YTHDF3YTHDF1JAK2 | |
| SCHEMBL27909964 | 0.70 | YTHDF2 (0.50) | PIK3C3YTHDF2YTHDF3YTHDF1JAK2 | |
| SCHEMBL6925607 | 0.68 | PDE4A (0.39) | PIK3C3YTHDF2YTHDF3YTHDF1JAK2 | |
| SCHEMBL6918752 | 0.67 | PIK3C3 (0.38) | PIK3C3YTHDF2YTHDF3YTHDF1JAK2 | |
| SCHEMBL19583295 | 0.66 | YTHDF2 (0.59) | PIK3C3YTHDF2YTHDF3YTHDF1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |