Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.65 |
| ▸ | HTR1D | P28221 | 3/20 | 0.65 |
| ▸ | HTR2B | P41595 | 3/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.65 |
| ▸ | DRD2 | P14416 | 2/20 | 0.65 |
| ▸ | DRD3 | P35462 | 2/20 | 0.65 |
| ▸ | HTR1B | P28222 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 2/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059602 | 0.91 | HTR7 (0.55) | HTR7HTR1DHTR2BHTR1ADRD2 | |
| SCHEMBL3825266 | 0.85 | HTR7 (0.69) | HTR7HTR1DHTR2BHTR1ADRD2 | |
| SCHEMBL6964528 | 0.85 | HTR7 (0.69) | HTR7HTR1DHTR2BHTR1ADRD2 | |
| SCHEMBL8308503 | 0.83 | HTR7 (0.84) | HTR7HTR1DHTR2BHTR1ADRD2 | |
| SCHEMBL699980 | 0.80 | HTR7 (0.63) | HTR7HTR1DHTR2BHTR1ADRD2 | |
| SCHEMBL6920928 | 0.80 | HCRTR1 (0.58) | HTR7HTR1DHTR2BHTR1ADRD2 | |
| SCHEMBL3825498 | 0.79 | HTR7 (1.00) | HTR7HTR1DHTR2BHTR1ADRD2 | |
| SCHEMBL5132145 | 0.79 | HTR7 (0.57) | HTR7HTR1DHTR2BHTR1ADRD2 | |
| SCHEMBL7967497 | 0.78 | HTR7 (0.74) | HTR7HTR1DHTR2BHTR1ADRD2 | |
| SCHEMBL15917086 | 0.77 | HTR6 (0.50) | HTR7HTR1DHTR2BHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041807-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-05-21 | — | — | WO | disclosed |