Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.58 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 8/20 | 0.54 |
| ▸ | HTR7 | P34969 | 5/20 | 0.54 |
| ▸ | HTR1D | P28221 | 3/20 | 0.54 |
| ▸ | HTR2B | P41595 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | CCR4 | P51679 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398899 | 0.92 | HCRTR1 (0.55) | HCRTR1HCRTR2MEN1KMT2ALMNA | |
| SCHEMBL2706418 | 0.84 | HCRTR1 (0.64) | HCRTR1HCRTR2MEN1KMT2ALMNA | |
| SCHEMBL2705837 | 0.84 | HCRTR1 (0.64) | HCRTR1HCRTR2MEN1KMT2ALMNA | |
| SCHEMBL6920929 | 0.80 | HTR7 (0.65) | HCRTR1HCRTR2MEN1KMT2ALMNA | |
| SCHEMBL8718942 | 0.78 | LMNA (0.58) | LMNAHTT | |
| SCHEMBL6964528 | 0.78 | HTR7 (0.69) | HCRTR1HCRTR2MEN1KMT2ACNR1 | |
| SCHEMBL14530359 | 0.77 | HSD11B1 (0.52) | HCRTR1HCRTR2LMNA | |
| SCHEMBL3974715 | 0.76 | EPHX2 (0.65) | MEN1KMT2ALMNACNR1EPHX2 | |
| SCHEMBL699980 | 0.76 | HTR7 (0.63) | HCRTR1HCRTR2MEN1KMT2ALMNA | |
| SCHEMBL4964697 | 0.75 | CNR1 (0.61) | MEN1KMT2ACNR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041807-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-05-21 | — | — | WO | disclosed |