Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.60 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.60 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.60 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.45 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KDM5C | P41229 | 3/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | KDM6B | O15054 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL8383301 | 1.00 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL8731618 | 0.97 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL6945727 | 0.93 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL5008156 | 0.93 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL5874334 | 0.93 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Adipic Acid SCHEMBL9949118 | 0.88 | LMNA (0.65) | LMNAOR51E2SLC22A6TSHRPMP22 | |
| Succinic Acid SCHEMBL5874145 | 0.85 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL5874137 | 0.85 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL18315815 | 0.84 | LMNA (0.43) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL140347 | 0.82 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515159-B2 | Useful as photographic bleaching agent, a fertilizer, biodegradability | MITSUBISHI RAYON CO., LTD. (JP) | 2003-02-04 | — | — | US | claimed |
| US-20150061942-A1 | TRANSLUCENT CONDUCTIVE PATTERNED MEMBER, AND TRANSLUCENT ELECTROMAGNETIC SHIELD - ANTENNA MEMBER USING SAME | Konica Minolta, Inc. (JP) | 2015-03-05 | — | — | US | disclosed |