Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.60 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.60 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.60 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.45 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KDM5C | P41229 | 3/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | KDM6B | O15054 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL6920955 | 1.00 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL8731618 | 0.97 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL6945727 | 0.93 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL5008156 | 0.93 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL5874334 | 0.93 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Adipic Acid SCHEMBL9949118 | 0.88 | LMNA (0.65) | LMNAOR51E2SLC22A6TSHRPMP22 | |
| Succinic Acid SCHEMBL5874145 | 0.85 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL5874137 | 0.85 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL18315815 | 0.84 | LMNA (0.43) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL140347 | 0.82 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044568-A1 | ANTIMICROBIAL POLYCARBONATE COATINGS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-02-29 | — | — | WO | claimed |
| EP-2681300-B1 | BROAD SPECTRUM DISINFECTANT | AMERICAN STERILIZER CO (US) | 2019-07-03 | — | — | EP | claimed |
| EP-2882433-B1 | ANTIMICROBIAL COMPOSITIONS COMPRISING GLYCERYL NITRATES | UNIV TEXAS (US) | 2019-03-13 | — | — | EP | claimed |
| US-20160374978-A1 | ANTIMICROBIAL COMPOSITIONS COMPRISING GLYCERYL NITRATES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-12-29 | — | — | US | claimed |
| US-9457002-B2 | Antimicrobial compositions comprising glyceryl nitrates | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-10-04 | — | — | US | claimed |
| US-20150196523-A1 | ANTIMICROBIAL COMPOSITIONS COMPRISING GLYCERYL NITRATES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-07-16 | — | — | US | claimed |
| EP-2882433-A1 | ANTIMICROBIAL COMPOSITIONS COMPRISING GLYCERYL NITRATES | Board Of Regents, The University Of Texas System (US) | 2015-06-17 | — | — | EP | claimed |
| WO-2014025994-A1 | ANTIMICROBIAL COMPOSITIONS COMPRISING GLYCERYL NITRATES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-02-13 | — | — | WO | claimed |
| US-8455551-B2 | Broad spectrum disinfectant | AMERICAN STERILIZER COMPANY (US) | 2013-06-04 | — | — | US | claimed |
| EP-0791083-B1 | METAL CLEANING AND DE-ICING COMPOSITIONS | ASS OCTEL (GB) | 1999-10-06 | — | — | EP | claimed |
| EP-0754249-B1 | USE OF A COMPOUND | ASS OCTEL (GB) | 1999-05-19 | — | — | EP | claimed |
| US-20240327676-A1 | POLISHING COMPOSITION, METHOD FOR PRODUCING SAME, AND POLISHING METHOD | FUJIMI INCORPORATED (JP) | 2024-10-03 | — | — | US | disclosed |
| WO-2024044568-A1 | ANTIMICROBIAL POLYCARBONATE COATINGS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-02-29 | — | — | WO | disclosed |
| US-11826332-B2 | Antimicrobial compositions and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-11-28 | — | — | US | disclosed |
| US-11065223-B2 | Antimicrobial compositions and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-07-20 | — | — | US | disclosed |
| US-5738914-A | EXPOSING THE SUBSTRATE WITH COPPER SULFATE COMPRISING ETHYLENE DIAMINE DISUCCINIC ACID BIODEGRADABLE CHELATE FOR METAL ION TO PREVENT OR REDUCE METAL HYDROXIDE PRECIPITES FORMING | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |
| EP-0791083-A2 | METAL CLEANING AND DE-ICING COMPOSITIONS | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1997-08-27 | — | — | EP | disclosed |
| EP-0754249-A1 | USE OF A COMPOUND | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1997-01-22 | — | — | EP | disclosed |
| WO-1996015293-A2 | METAL CLEANING AND DE-ICING COMPOSITIONS | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1996-05-23 | — | — | WO | disclosed |
| WO-1996015290-A1 | USE OF A COMPOUND | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1996-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11065223-B2 | Antimicrobial compositions and uses thereof | FUT6, FUT5, IDUA | LMNA 3616/4885EGLN1 790/4885ALKBH5 1424/4885 |
| US-11826332-B2 | Antimicrobial compositions and uses thereof | FUT6, FUT5, IDUA | LMNA 3616/4885EGLN1 790/4885ALKBH5 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.