Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.39 |
| ▸ | ITGAL | P20701 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218242 | 0.88 | ITGAL (0.52) | L3MBTL1MAPTITGB2ICAM1ITGAL | |
| SCHEMBL6921378 | 0.87 | MAPT (0.52) | L3MBTL1MAPTLMNASMN1; SMN2RAB9A | |
| SCHEMBL6919351 | 0.86 | SMN1; SMN2 (0.53) | L3MBTL1MAPTITGB2ICAM1ITGAL | |
| SCHEMBL6921585 | 0.84 | NPC1 (0.42) | L3MBTL1MAPTITGB2ICAM1ITGAL | |
| SCHEMBL6918094 | 0.83 | RAB9A (0.56) | L3MBTL1ITGB2ICAM1ITGALSMN1; SMN2 | |
| SCHEMBL6918679 | 0.81 | GPR183 (0.53) | L3MBTL1MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL6222441 | 0.80 | MAPT (0.40) | L3MBTL1MAPTITGB2ICAM1ITGAL | |
| SCHEMBL6817246 | 0.79 | F2R (0.42) | L3MBTL1MAPTSMN1; SMN2POLBGAA | |
| SCHEMBL6919430 | 0.79 | RAB9A (0.39) | L3MBTL1MAPTITGB2ICAM1ITGAL | |
| SCHEMBL7619041 | 0.77 | LMNA (0.46) | L3MBTL1LMNASMN1; SMN2GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |