Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GPR183 | P32249 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918679 | 0.88 | GPR183 (0.53) | F2RMAPTL3MBTL1KMT2ATDP1 | |
| SCHEMBL6921378 | 0.83 | MAPT (0.52) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6221015 | 0.81 | ALPL (0.47) | F2RMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL6918094 | 0.80 | RAB9A (0.56) | L3MBTL1TDP1ALDH1A1HPGDRAB9A | |
| SCHEMBL6921387 | 0.79 | L3MBTL1 (0.42) | MAPTL3MBTL1KMT2AMEN1GAA | |
| SCHEMBL7064160 | 0.77 | F2R (0.38) | F2RMAPTL3MBTL1KMT2AGPR183 | |
| SCHEMBL6218242 | 0.77 | ITGAL (0.52) | MAPTL3MBTL1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL6919351 | 0.76 | SMN1; SMN2 (0.53) | MAPTL3MBTL1ALDH1A1RAB9APOLB | |
| SCHEMBL6919430 | 0.76 | RAB9A (0.39) | F2RMAPTL3MBTL1TDP1GAA | |
| SCHEMBL6817245 | 0.75 | ALDH1A1 (0.39) | MAPTGAAALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | disclosed |