Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ITGAL | P20701 | 5/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921378 | 0.88 | MAPT (0.52) | RAB9ANPC1L3MBTL1KDM4EHPGD | |
| SCHEMBL6921387 | 0.83 | L3MBTL1 (0.42) | RAB9ANPC1L3MBTL1KDM4EHPGD | |
| SCHEMBL6918679 | 0.82 | GPR183 (0.53) | L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6218242 | 0.81 | ITGAL (0.52) | RAB9ANPC1L3MBTL1ITGALITGB2 | |
| SCHEMBL6817246 | 0.80 | F2R (0.42) | RAB9AL3MBTL1TDP1HPGDPOLB | |
| SCHEMBL6919351 | 0.80 | SMN1; SMN2 (0.53) | RAB9ANPC1L3MBTL1KDM4EITGAL | |
| SCHEMBL6919430 | 0.80 | RAB9A (0.39) | RAB9ANPC1L3MBTL1TDP1HPGD | |
| SCHEMBL6921585 | 0.78 | NPC1 (0.42) | RAB9ANPC1L3MBTL1ITGALITGB2 | |
| SCHEMBL7641657 | 0.76 | ITGAL (0.76) | RAB9ANPC1L3MBTL1TDP1KDM4E | |
| SCHEMBL6920036 | 0.76 | ITGAL (0.76) | RAB9ANPC1L3MBTL1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | claimed |
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | disclosed |