Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | HTR1D | P28221 | 1/20 | 0.58 |
| ▸ | HTR1B | P28222 | 1/20 | 0.58 |
| ▸ | HTR1E | P28566 | 1/20 | 0.58 |
| ▸ | HTR1F | P30939 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919423 | 0.87 | HTR6 (0.53) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL6921381 | 0.87 | MTNR1A (0.57) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL6833442 | 0.84 | ADRB2 (0.67) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL24878488 | 0.82 | HTR6 (0.68) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL20307221 | 0.81 | HTR6 (1.00) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL20307243 | 0.80 | HTR6 (0.88) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL29261918 | 0.80 | HTR6 (0.73) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL25330502 | 0.80 | HTR6 (0.73) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL24877632 | 0.80 | HTR6 (0.75) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL30859492 | 0.80 | HTR6 (0.75) | HTR6HTR1ADRD2HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085392-A1 | MELATONIN DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL DYSFUNCTIONS | FAUST PHARMACEUTICALS (FR) | 2004-10-07 | — | — | WO | disclosed |