Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.67 |
| ▸ | HTR6 | P50406 | 11/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921659 | 0.84 | HTR6 (0.68) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL6833440 | 0.82 | PLA2G2A (0.61) | ADRB2MTNR1ANQO2MTNR1B | |
| SCHEMBL6949412 | 0.81 | MTNR1A (0.49) | ADRB2HTR6MTNR1ANQO2MTNR1B | |
| SCHEMBL28121087 | 0.81 | ADRB2 (0.67) | ADRB2HTR6HTR2ACYP1A2HTR1A | |
| SCHEMBL194360 | 0.80 | MTNR1A (0.73) | CYP1A2HTR1AHTR2CBLMPMP22 | |
| SCHEMBL1130016 | 0.80 | ADRB2 (1.00) | ADRB2HTR6HTR2ACYP1A2HTR1A | |
| SCHEMBL6938945 | 0.79 | MTNR1A (0.58) | MTNR1ANQO2MTNR1B | |
| SCHEMBL6919423 | 0.79 | HTR6 (0.53) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL6921381 | 0.79 | MTNR1A (0.57) | HTR6HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL10482825 | 0.79 | ADRB2 (0.72) | ADRB2HTR6HTR2ACYP1A2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085392-A1 | MELATONIN DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL DYSFUNCTIONS | FAUST PHARMACEUTICALS (FR) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004085395-A1 | MELATONIN DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL DYSFUNCTIONS | FAUST PHARMACEUTICALS (FR) | 2004-10-07 | — | — | WO | disclosed |