Aristeromycin

Aristeromycin

SCHEMBL29695815

Nc1ncnc2c1ncn2[C@@H]1C[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AHCY P23526 16/20 1.00
ADORA2B P29275 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aristeromycin SCHEMBL10353292 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL12280589 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL10353291 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL14515457 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL12173988 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL7534801 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL9820408 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL12157242 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL692209 1.00 AHCY (1.00) AHCYADORA2B
SCHEMBL15297972 0.99 AHCY (0.97) AHCYADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435088-B2 Salicyl-adenosinemonosulfamate analogs and uses thereof MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2025-10-07 US disclosed
US-20250228855-A1 PYRAZINAMIDE COMPOUNDS MASSACHUSETTS GEN HOSPITAL (US) 2025-07-17 US disclosed
US-20250093263-A1 FRET-BASED ASSAYS THE GENERAL HOSPITAL CORPORATION 2025-03-20 US disclosed
EP-4374157-A2 FRET-BASED ASSAYS The General Hospital Corporation (US) 2024-05-29 EP disclosed
CN-117797146-A SARM1 enzyme activity inhibitors and their use in neurodegenerative diseases 科辉智药生物科技(无锡)有限公司 2024-04-02 CN disclosed
WO-2023205272-A1 PYRAZINAMIDE COMPOUNDS THE GENERAL HOSPITAL CORPORATION (US) 2023-10-26 WO disclosed
US-20230233497-A1 COMPOSITION FOR POLYAMINE BIOSYNTHESIS BM HEALTH GMBH (AT) 2023-07-27 US disclosed
CN-115814270-A Electrical stimulator 中国科学院深圳理工大学(筹) 2023-03-21 CN disclosed
WO-2023004438-A2 FRET-BASED ASSAYS THE GENERAL HOSPITAL CORPORATION (US) 2023-01-26 WO disclosed
EP-4114380-A1 COMPOSITION FOR POLYAMINE BIOSYNTHESIS BM Health GmbH (AT) 2023-01-11 EP disclosed
EP-4100112-A1 FUNCTION OPTIMIZATION ALGORITHM AND MULTI-TYPE ELECTROTHERAPY COMBINATION TREATMENT Malter, Richard (AU) 2022-12-14 EP disclosed
US-20220387796-A1 ELECTRICAL STIMULATION METHOD FOR MEDICAL TREATMENT MALTER RICHARD (AU) 2022-12-08 US disclosed
US-20220162209-A1 SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2022-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220162209-A1 SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF ADSL, SLC35B2, ADORA1 AHCY 44/4885ADORA2B 10/4885
US-12435088-B2 Salicyl-adenosinemonosulfamate analogs and uses thereof ADSL, SLC35B2, ADORA1 AHCY 44/4885ADORA2B 10/4885
US-20250093263-A1 FRET-BASED ASSAYS TARBP1, GTPBP4, TERF2IP AHCY 818/4885ADORA2B 2861/4885
US-20250228855-A1 PYRAZINAMIDE COMPOUNDS PC, GOT2, PCK2 AHCY 2564/4885ADORA2B 4410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.