Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 6/20 | 0.62 |
| ▸ | RORC | P51449 | 6/20 | 0.62 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.60 |
| ▸ | RORB | Q92753 | 2/20 | 0.52 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817824 | 0.79 | RORA (0.68) | RORARORCNR1H2NR1H4NR1H3 | |
| SCHEMBL31078033 | 0.79 | RORA (0.68) | RORARORCNR1H2NR1H4NR1H3 | |
| SCHEMBL12334079 | 0.77 | RORA (1.00) | RORARORCNR1H2NR1H4NR1H3 | |
| SCHEMBL6922110 | 0.76 | RORC (0.64) | RORARORCNR1H2NR1H4NR1H3 | |
| SCHEMBL2415124 | 0.76 | NR1H3 (1.00) | RORARORCNR1H2NR1H4NR1H3 | |
| SCHEMBL6922105 | 0.75 | RORA (0.62) | RORARORCNR1H2NR1H4NR1H3 | |
| SCHEMBL2944332 | 0.71 | NR1H3 (0.66) | RORARORCNR1H2NR1H4NR1H3 | |
| SCHEMBL12334557 | 0.71 | NR1H3 (0.84) | RORARORCNR1H2NR1H4NR1H3 | |
| SCHEMBL12334070 | 0.71 | ALDH1A1 (0.67) | RORARORCNR1H2NR1H4NR1H3 | |
| SCHEMBL12334066 | 0.70 | RORA (1.00) | RORARORCNR1H2NR1H4NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723893-A1 | NEW TH-17 DIFFERENTIATION MARKERS FOR ROSACEA AND USES THEREOF | Galderma Research & Development (FR) | 2014-04-30 | — | — | EP | claimed |
| WO-2013000871-A1 | NEW TH-17 DIFFERENTIATION MARKERS FOR ROSACEA AND USES THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-01-03 | — | — | WO | claimed |
| WO-2004072046-A2 | QUINOLINE DERIVATIVES AND THEIR USE FOR MODULATION OF LXR ACTIVITY | CAREX S.A. (FR) | 2004-08-26 | — | — | WO | disclosed |
| WO-2004072042-A2 | QUINOLINE DERIVATIVE AND THEIR USE FOR MODULATION OF LXR ACTIVITY | CAREX S.A. (FR) | 2004-08-26 | — | — | WO | disclosed |