Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7249971 | 0.76 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL4728649 | 0.72 | ALDH1A1 (0.54) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL10567759 | 0.70 | ALDH1A1 (0.50) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL10474720 | 0.69 | ALDH1A1 (0.53) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL28461199 | 0.68 | PABPC1 (0.45) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL7204453 | 0.68 | ALDH1A1 (0.60) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL11329048 | 0.68 | ALDH1A1 (0.49) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL28474638 | 0.67 | PDGFRA (0.44) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL38652869 | 0.67 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL4337410 | 0.67 | ALOX15 (0.47) | MAPTALDH1A1KDM4EPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111052-A1 | PYRROLOPYRIMIDINE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE (MDR) | XENOVA LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |