Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA1 | P56199 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925435 | 0.91 | ALDH1A1 (0.55) | ALDH1A1LMNAPOLBKMT2AHSD17B10 | |
| SCHEMBL6922338 | 0.88 | POLB (0.56) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL3071479 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LMNAPOLBKMT2AHSD17B10 | |
| SCHEMBL6922336 | 0.86 | ALDH1A1 (0.56) | ALDH1A1LMNAPOLBKMT2AHSD17B10 | |
| SCHEMBL3069679 | 0.85 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLB | |
| SCHEMBL6920069 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL6923759 | 0.82 | POLB (0.57) | ALDH1A1LMNAPOLB | |
| SCHEMBL6920999 | 0.82 | PKLR (0.48) | ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL6828029 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBKMT2AHSD17B10 | |
| SCHEMBL3075154 | 0.81 | PKM (0.59) | ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | disclosed |