Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 3/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920933 | 0.73 | PARP1 (0.44) | ALDH1A1HDAC6DHFR | |
| SCHEMBL6967049 | 0.70 | LMNA (0.37) | ALDH1A1MAPTLMNATDP1POLB | |
| SCHEMBL6961420 | 0.66 | DHFR (0.36) | ALDH1A1MAPTLMNAKMT2AHDAC6 | |
| SCHEMBL6967253 | 0.64 | TUBB4A (0.32) | ALDH1A1TDP1POLBKMT2ADHFR | |
| SCHEMBL7081802 | 0.62 | DHFR (0.39) | LMNAKMT2AKDM4EDHFRSLC6A4 | |
| SCHEMBL6967042 | 0.62 | KMT2A (0.37) | ALDH1A1MAPTLMNATDP1POLB | |
| SCHEMBL1284420 | 0.62 | TAAR1 (0.59) | ALDH1A1POLBKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL24486045 | 0.62 | KDM4E (0.49) | ALDH1A1LMNASMN1; SMN2L3MBTL1KDM4E | |
| Diphenylsulfane SCHEMBL28246047 | 0.62 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNATDP1POLB | |
| SCHEMBL6961413 | 0.61 | SMN1; SMN2 (0.39) | ALDH1A1MAPTLMNATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074258-A1 | NOVEL SULPHATED IMIDAZOLE DERIVATIVES, METHOD FOR PRODUCTION THEREOF, NOVEL INTERMEDIATES OBTAINED, APPLICATION THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE ABOVE | CAILLE JEAN-CLAUDE (FR) | 2004-09-02 | — | — | WO | disclosed |
| EP-0465368-B1 | Sulfur derivatives of imidazole, process for their preparation, intermediates, their use as medicaments, and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 1998-05-20 | — | — | EP | disclosed |
| EP-0465368-A1 | Sulfur derivatives of imidazole, process for their preparation, intermediates, their use as medicaments, and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-01-08 | — | — | EP | disclosed |