Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920933 | 0.70 | PARP1 (0.44) | ALDH1A1 | |
| SCHEMBL6866633 | 0.70 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL6961413 | 0.69 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL14546056 | 0.68 | AGTR1 (0.31) | AGTR1AGTR2 | |
| SCHEMBL7084560 | 0.66 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL6967042 | 0.65 | KMT2A (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL13263650 | 0.64 | MAPT (0.69) | GLASMN1; SMN2 | |
| SCHEMBL6919672 | 0.64 | PARP1 (0.46) | ALDH1A1 | |
| SCHEMBL27896025 | 0.63 | DRD2 (0.46) | AGTR1AGTR2HSD11B1ALDH1A1 | |
| SCHEMBL1784723 | 0.62 | SLC6A4 (0.50) | SMN1; SMN2HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074258-A1 | NOVEL SULPHATED IMIDAZOLE DERIVATIVES, METHOD FOR PRODUCTION THEREOF, NOVEL INTERMEDIATES OBTAINED, APPLICATION THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE ABOVE | CAILLE JEAN-CLAUDE (FR) | 2004-09-02 | — | — | WO | disclosed |