⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28545763 | 0.89 | P2RX7 (0.33) | — | |
| Pyrimidine SCHEMBL29159522 | 0.89 | CYP2A6 (0.31) | — | |
| Imidazole SCHEMBL7473586 | 0.80 | ALDH1A1 (0.46) | — | |
| Hypoxanthine SCHEMBL5677270 | 0.76 | ALDH1A1 (0.58) | — | |
| SCHEMBL2162432 | 0.76 | — | — | |
| SCHEMBL15428791 | 0.75 | MEN1 (0.38) | — | |
| SCHEMBL10864413 | 0.74 | DBH (0.33) | — | |
| SCHEMBL3848 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL7957885 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL4436012 | 0.67 | LMNA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 705 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124910-A1 | RIBOSOME-MEDIATED POLYMERIZATION OF NOVEL CHEMISTRIES | NORTHWESTERN UNIVERSITY | 2024-04-18 | — | — | US | claimed |
| US-20240116939-A1 | CHIRAL OR RACEMIC PYRIMIDINE-FUSED DIAZEPINONE DERIVATIVES, PREPARATION METHOD, AND APPLICATION THEREOF | SUN YAT-SEN UNIVERSITY (CN) | 2024-04-11 | — | — | US | claimed |
| CN-113004186-B | Zinc-ligand azapyrrolidone photo-diagnosis and treatment reagent with long-wave absorption characteristic and preparation and application thereof | 南京邮电大学 | 2022-12-30 | — | — | CN | claimed |
| CN-111819181-A | Benzo-seven-membered heterocyclic compound, preparation method, pharmaceutical composition and application thereof | 罗欣药业(上海)有限公司 | 2020-10-23 | — | — | CN | claimed |
| EP-1670809-B1 | SYNTHESIS AND MANUFACTURE OF PENTOSTATIN AND ITS PRECURSORS, ANALOGS AND DERIVATIVES | MAYNE PHARMA PLC (GB) | 2016-01-13 | — | — | EP | claimed |
| EP-1966212-B1 | DIAZEPINONES | MERCK PATENT GMBH (DE) | 2015-05-13 | — | — | EP | claimed |
| US-20140275042-A1 | TRICYCLIC AND TETRACYCLIC SYSTEMS ACTING UPON THE VASCULAR AND CENTRAL NERVOUS SYSTEMS | VERDECIA REYES YAMILA (CU) | 2014-09-18 | — | — | US | claimed |
| JP-4830128-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| US-7943608-B2 | Diazepinoes | MERCK PATENT GMBH (DE) | 2011-05-17 | — | — | US | claimed |
| CN-101440066-A | Benzodiazepinic amine nitrite compound, preparation and use thereof | QILU TIANHEHUISHI PHARMACEUTIC (CN) | 2009-05-27 | — | — | CN | claimed |
| EP-0344543-A2 | Condensed diazepinones, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1989-12-06 | — | — | EP | claimed |
| EP-0326066-A2 | Condensed diazepinones, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1989-08-02 | — | — | EP | claimed |
| EP-0156191-B1 | CONDENSED DIAZEPINONES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1989-07-19 | — | — | EP | claimed |
| EP-0312895-A2 | Condensed diazepinones, process for their preparation and medicament containing them | Dr. Karl Thomae GmbH (DE) | 1989-04-26 | — | — | EP | claimed |
| EP-0306698-A1 | Condensed diazepinones, processes for their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1989-03-15 | — | — | EP | claimed |
| EP-0273239-A1 | Condensed diazepinones, processes for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1988-07-06 | — | — | EP | claimed |
| US-4705853-A | ANTIHISTAMINES | A. H. ROBINS COMPANY, INC. (US) | 1987-11-10 | — | — | US | claimed |
| US-4642343-A | ANTIHISTAMINES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-02-10 | — | — | US | claimed |
| EP-0156191-A2 | Condensed diazepinones, process for their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-10-02 | — | — | EP | claimed |
| WO-1981000568-A1 | BENZODIAZEPINONES,A PROCESS FOR THEIR PREPARATION,THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1981-03-05 | — | — | WO | claimed |