Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | BLK | P51451 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | STK3 | Q13188 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692243 | 0.80 | — | — | |
| Pyridazine SCHEMBL527648 | 0.76 | ALDH1A1 (0.72) | ALDH1A1FKBP5 | |
| Pyridazine SCHEMBL29463271 | 0.76 | ALDH1A1 (0.72) | ALDH1A1FKBP5 | |
| Pyrimidine SCHEMBL29159522 | 0.75 | CYP2A6 (0.31) | PLK4AURKACHEK2LCKCDK2 | |
| Anthraquinone SCHEMBL22345157 | 0.73 | ALDH1A1 (0.54) | ALDH1A1FKBP5 | |
| Naphthalene SCHEMBL338629 | 0.72 | ALDH1A1 (0.65) | ALDH1A1FKBP5CDK2MAPK8 | |
| Naphthalene SCHEMBL2123892 | 0.72 | ALDH1A1 (0.65) | ALDH1A1FKBP5CDK2MAPK8 | |
| Formic Acid SCHEMBL28545763 | 0.71 | P2RX7 (0.33) | PLK4AURKACHEK2LCKCDK2 | |
| Imidazole SCHEMBL10402410 | 0.70 | FKBP5 (0.61) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL6429007 | 0.70 | ALDH1A1 (0.50) | ALDH1A1FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117940-A | SOLID PHASE SYNTHESIS OF COMPOUNDS SUCH AS THE IMIDAZOLES, BENZODIAZEPINES, PYRAZINES, AND STEROID MIMICS. | ADVANCED SYNTECH, LLC, A KENTUCKY LIMITED LIABILITY CORPORATION | 2000-09-12 | — | — | US | claimed |
| EP-1153050-A4 | AMINO-KETONE SOLID SUPPORT TEMPLATES | ADVANCED SYNTECH LLC (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-1153050-A1 | AMINO-KETONE SOLID SUPPORT TEMPLATES | Advanced syntech, LLC (US) | 2001-11-14 | — | — | EP | disclosed |
| US-6117940-A | SOLID PHASE SYNTHESIS OF COMPOUNDS SUCH AS THE IMIDAZOLES, BENZODIAZEPINES, PYRAZINES, AND STEROID MIMICS. | ADVANCED SYNTECH, LLC, A KENTUCKY LIMITED LIABILITY CORPORATION | 2000-09-12 | — | — | US | disclosed |
| WO-2000023487-A1 | AMINO-KETONE SOLID SUPPORT TEMPLATES | ADVANCED SYNTECH, LLC (US) | 2000-04-27 | — | — | WO | disclosed |