Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.87 |
| ▸ | RAB9A | P51151 | 5/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ME2 | P23368 | 1/20 | 0.61 |
| ▸ | ME1 | P48163 | 1/20 | 0.61 |
| ▸ | ME3 | Q16798 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692605 | 1.00 | MEN1 (0.87) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL692499 | 1.00 | MEN1 (0.87) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL28112899 | 1.00 | MEN1 (0.87) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL692258 | 0.98 | MEN1 (0.90) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL692257 | 0.98 | MEN1 (0.90) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL16599448 | 0.91 | KMT2A (0.89) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL4456981 | 0.91 | KMT2A (0.89) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL16599447 | 0.91 | KMT2A (0.89) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL29738475 | 0.88 | KMT2A (0.69) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL30853516 | 0.88 | KMT2A (0.69) | MEN1KMT2ARAB9APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710892-B1 | Use of sarmentine and its analogs for controlling weeds | MARRONE BIO INNOVATIONS INC (US) | 2016-12-14 | — | — | EP | claimed |
| EP-2918271-A1 | Aromatic alkenoic acid derivatives as aroma compounds | Symrise AG (DE) | 2015-09-16 | — | — | EP | claimed |
| EP-2710892-A2 | Use of sarmentine and its analogs for controlling plant pests | Marrone Bio Innovations, Inc. (US) | 2014-03-26 | — | — | EP | claimed |
| US-20130196013-A1 | CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS | MARRONE BIO INNOVATIONS, INC. (US) | 2013-08-01 | — | — | US | claimed |
| EP-2601840-A2 | Chemical and biological agents for the control of molluscs | Marrone Bio Innovations, Inc. (US) | 2013-06-12 | — | — | EP | claimed |
| US-20130121978-A1 | CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS | MARRONE BIO INNOVATIONS, INC. (US) | 2013-05-16 | — | — | US | claimed |
| EP-2421375-A2 | CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS | Marrone Bio Innovations, Inc. (US) | 2012-02-29 | — | — | EP | claimed |
| WO-2010123894-A2 | CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS | MARRONE BIO INNOVATIONS, INC. (US) | 2010-10-28 | — | — | WO | claimed |
| US-20100266717-A1 | CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS | MARRONE BIO INNOVATIONS, INC. (US) | 2010-10-21 | — | — | US | claimed |
| CN-101808635-A | Use of piperine and derivatives thereof for the therapy of neurological conditions | SYGNIS BIOSCIENCE GMBH & CO KG | 2010-08-18 | — | — | CN | claimed |
| US-20100179130-A1 | USE OF PIPERINE AND DERIVATIVES THEREOF FOR THE THERAPY OF NEUROLOGICAL CONDITIONS | SYNGIS Bioscience GmbH & Co. KG (DE) | 2010-07-15 | — | — | US | claimed |
| EP-2170320-A1 | USE OF PIPERINE AND DERIVATIVES THEREOF FOR THE THERAPY OF NEUROLOGICAL CONDITIONS | Sygnis Bioscience GmbH & Co. KG (DE) | 2010-04-07 | — | — | EP | claimed |
| WO-2009004071-A1 | USE OF PIPERINE AND DERIVATIVES THEREOF FOR THE THERAPY OF NEUROLOGICAL CONDITIONS | SYGNIS BIOSCIENCE GMBH & CO. KG (DE) | 2009-01-08 | — | — | WO | claimed |
| EP-2011495-A1 | Use of piperine and derivatives thereof for the therapy of neurological conditions | Sygnis Bioscience GmbH & Co. KG (DE) | 2009-01-07 | — | — | EP | claimed |
| US-20240336869-A1 | MICROWAVE ASSISTED EXTRACTION OF ESSENTIAL OILS FROM PLANT BIOMASS | FIRMENICH SA (CH) | 2024-10-10 | — | — | US | disclosed |
| US-12054692-B2 | Microwave assisted extraction of essential oils from plant biomass | FIRMENICH SA (CH) | 2024-08-06 | — | — | US | disclosed |
| CN-116444370-A | Preparation method of alpha, beta-unsaturated carboxylic acid derivative | 大连理工常熟研究院有限公司 | 2023-07-18 | — | — | CN | disclosed |
| EP-0157399-B1 | 4-(5H-Dibenzo[a,d]cyclohepten-5-yl) piperidine compounds | MERCK & CO. INC. (US) | 1989-08-16 | — | — | EP | disclosed |
| US-4758577-A | 4-(5H-dibenzo[a,d]cyclohepten-5-yl)piperidine compounds for treating cardiovascular disorders | MERCK & CO., INC. (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0157399-A2 | 4-(5H-Dibenzo[a,d]cyclohepten-5-yl) piperidine compounds | MERCK & CO. INC. (US) | 1985-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100266717-A1 | CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS | ACHE, POLI, POLL | MEN1 3759/4885KMT2A 1501/4885RAB9A 448/4885 |
| US-20130196013-A1 | CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS | ACHE, POLI, POLL | MEN1 3759/4885KMT2A 1501/4885RAB9A 448/4885 |
| US-20100179130-A1 | USE OF PIPERINE AND DERIVATIVES THEREOF FOR THE THERAPY OF NEUROLOGICAL CONDITIONS | PRPH, BDNF, GAP43 | MEN1 3003/4885KMT2A 1722/4885RAB9A 803/4885 |
| US-20130121978-A1 | CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS | ACHE, POLI, POLL | MEN1 3759/4885KMT2A 1501/4885RAB9A 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.