Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15249458 | 0.97 | GPR84 (0.43) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL12851375 | 0.97 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL2718891 | 0.91 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5972273 | 0.91 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL1557044 | 0.91 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8469082 | 0.91 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL2702837 | 0.91 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL1027845 | 0.91 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5972279 | 0.91 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL17480708 | 0.91 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156029-B1 | Derivatives of acetoacetic acid, their process of preparation and their use | BASF AG (DE) | 2003-06-18 | — | — | EP | disclosed |
| US-6515154-B2 | Acetoacetic acid derivatives, process for their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-04 | — | — | US | disclosed |
| US-20010056195-A1 | Acetoacetic acid derivatives, process for their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-27 | — | — | US | disclosed |
| EP-1156029-A1 | Derivatives of acetoacetic acid, their process of preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056195-A1 | Acetoacetic acid derivatives, process for their preparation and their use | ACMSD, MLYCD, HADHB | GPR84 3106/4885FFAR1 50/4885MAPT 4198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.