SCHEMBL1557044

SCHEMBL1557044

CCCCCCCCCCCCCCC(C(C)=O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.59
FFAR1 O14842 2/20 0.59
MAPT P10636 1/20 0.57
LCK P06239 1/20 0.57
PPARD Q03181 1/20 0.57
ZDHHC20 Q5W0Z9 1/20 0.57
ZDHHC2 Q9UIJ5 1/20 0.57
ACE2 Q9BYF1 1/20 0.53
GRIK1 P39086 2/20 0.48
GRIK2 Q13002 2/20 0.48
FFAR4 Q5NUL3 1/20 0.48
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7461114 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL27456709 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL5972273 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL2718891 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL1027845 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8469082 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL2702837 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL17480708 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL5972279 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD
SCHEMBL3625304 1.00 GPR84 (0.59) GPR84FFAR1MAPTLCKPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009101412-A1 TOPICAL PHARMACEUTICAL COMPOSITION CIPLA LIMITED (IN) 2009-08-20 WO claimed
CN-122028939-A Thyroid hormone delivery system comprising lipid or polymer nanoparticles 里卡尔多·泰尔齐与西尔维奥·阿尔比尼基金会 2026-05-12 CN disclosed
CN-119072463-A Novel ionizable cationic lipids 维硕公司 2024-12-03 CN disclosed
CN-114929205-B Lipid nanoparticle compositions comprising end-capped DNA and cleavable lipids and methods of use thereof 世代生物公司 2024-09-03 CN disclosed
CN-116437964-A Methods for encapsulating polynucleotides into reduced size lipid nanoparticles and novel formulations thereof 世代生物公司 2023-07-14 CN disclosed
CN-116171150-A Method for lyophilizing lipid nanoparticles 阿克丘勒斯治疗公司 2023-05-26 CN disclosed
CN-115697321-A Cationic lipids for lipid nanoparticles for delivering therapeutic agents to hepatic stellate cells 盖纳万科学有限公司 2023-02-03 CN disclosed
CN-115516090-A TREM compositions and uses thereof 旗舰先锋创新VI有限责任公司 2022-12-23 CN disclosed
CN-115397984-A Recombinase compositions and methods of use 旗舰先锋创新VI有限责任公司 2022-11-25 CN disclosed
CN-115003312-A High density lipoprotein-like nanoparticles as inducers of iron death in cancer 西北大学 2022-09-02 CN disclosed
US-6733777-B2 CYTOFECTINS; SUPPLYING EXOGENOUS COMPOUNDS INTO CELLS QIAGEN GMBH (DE) 2004-05-11 US disclosed
US-20040077582-A1 Cationic reagents for transfection ERBACHER CHRISTOPH (DE) 2004-04-22 US disclosed
US-20030229013-A1 Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) 2003-12-11 US disclosed
US-20030229017-A1 Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same DEVELOPMENT CENTER FOR BIOTECHNOLOGY 2003-12-11 US disclosed
EP-1319667-A2 Solid phase method for the synthesis of peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) 2003-06-18 EP disclosed
US-6458381-B1 COMPLEXING LYSINE-BIS-(O,O*-9-OCTADECENOYL-B-HYDROXYETHYL) AMIDE WITH LIPID, RNA, DNA, OR POLYPEPTIDE Sourovoi, Andrej (RU) 2002-10-01 US disclosed
US-20010048939-A1 Cytofectins; supplying exogenous compounds into cells QIAGEN GMBH (DE) 2001-12-06 US disclosed
EP-1003556-A2 CATIONIC REAGENTS FOR TRANSFECTION QIAGEN GmbH (DE) 2000-05-31 EP disclosed
WO-1998019709-A2 CATIONIC REAGENTS FOR TRANSFECTION QIAGEN GMBH (DE) 1998-05-14 WO disclosed
EP-0143881-A2 Process for the preparation of an alkyl ester of L-alpha-aspartyl-L-phenyl-alanine GEMA S.A. (ES) 1985-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030229013-A1 Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same DLST, LNPEP, LSS GPR84 1551/4885FFAR1 1324/4885MAPT 4301/4885
US-20030229017-A1 Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same DLST, LNPEP, LSS GPR84 1551/4885FFAR1 1324/4885MAPT 4301/4885
US-20010048939-A1 Cytofectins; supplying exogenous compounds into cells PHOSPHO1, CYTH2, PCTP GPR84 2312/4885FFAR1 1854/4885MAPT 4828/4885
US-20040077582-A1 Cationic reagents for transfection PHOSPHO1, PCTP, CYTH2 GPR84 2755/4885FFAR1 2933/4885MAPT 4797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.