Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925787 | 0.79 | PARP1 (0.54) | MAPTPOLBRAB9ANR4A1ALDH1A1 | |
| SCHEMBL7592576 | 0.79 | KDR (0.47) | CRBNMAPTITGB3ITGAVITGA2B | |
| SCHEMBL17214946 | 0.75 | NQO2 (0.49) | MAPTPOLBRAB9AALDH1A1HSD17B10 | |
| SCHEMBL10294635 | 0.74 | POLB (0.58) | CRBNMAPTPOLBRAB9ANR4A1 | |
| SCHEMBL12402234 | 0.72 | NPC1 (0.47) | POLBRAB9ARETALDH1A1CYP1A2 | |
| SCHEMBL18518257 | 0.72 | POLB (0.55) | CRBNMAPTPOLBRAB9ANR4A1 | |
| SCHEMBL6694019 | 0.71 | MAPT (0.59) | MAPTPOLBRAB9AALDH1A1CYP1A2 | |
| SCHEMBL17324145 | 0.70 | ALDH1A1 (0.61) | MAPTPOLBRAB9ANR4A1ALDH1A1 | |
| SCHEMBL13836493 | 0.70 | ALDH1A1 (0.61) | MAPTPOLBRAB9ANR4A1ALDH1A1 | |
| SCHEMBL4213610 | 0.70 | PPARG (0.50) | CRBNMAPTPOLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101533-A1 | 1, 3, 4-BENZOTRIAZEPIN-2-ONE SALTS AND THEIR USE AS CCK RECEPTOR LIGANDS | JANSSEN PHARMACEUTICA, N.V. (US) | 2004-11-25 | — | — | WO | disclosed |