Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | NEK2 | P51955 | 1/20 | 0.48 |
| ▸ | MAPK15 | Q8TD08 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22167182 | 0.88 | MGLL (0.54) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9314587 | 0.87 | MGLL (0.45) | MAPTALDH1A1SMN1; SMN2TP53KDM4E | |
| SCHEMBL9573406 | 0.86 | MAPT (0.43) | MAPTALDH1A1SMN1; SMN2TP53KDM4E | |
| SCHEMBL950001 | 0.85 | CYP3A4 (0.60) | MAPTALDH1A1SMN1; SMN2TP53KDM4E | |
| Acitazanolast SCHEMBL342549 | 0.84 | GPR35 (0.54) | MAPTALDH1A1SMN1; SMN2TP53KDM4E | |
| SCHEMBL15094744 | 0.84 | KMT2A (0.49) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL730434 | 0.84 | FYN (0.50) | MAPTALDH1A1SMN1; SMN2TP53KDM4E | |
| Acitazanolast SCHEMBL3116621 | 0.83 | GPR35 (0.53) | MAPTALDH1A1SMN1; SMN2TP53KDM4E | |
| SCHEMBL12892198 | 0.82 | SMN1; SMN2 (0.56) | MAPTALDH1A1SMN1; SMN2TP53KDM4E | |
| SCHEMBL956335 | 0.81 | HPGD (0.60) | MAPTALDH1A1SMN1; SMN2TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248950-A1 | Apo ai expression accelerating agent | SHIONOGI & CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1419770-A1 | APO AI EXPRESSION ACCELERATING AGENT | SHIONOGI & CO., LTD. (JP) | 2004-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248950-A1 | Apo ai expression accelerating agent | APOB, APOL1, NR1H2 | MAPT 4864/4885ALDH1A1 2204/4885SMN1; SMN2 1789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.