SCHEMBL692384

SCHEMBL692384

CCOC(=O)C1=CC(=O)N=N1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
TSHR P16473 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 5/20 0.40
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA7 P43166 3/20 0.40
CA9 Q16790 3/20 0.40
CA14 Q9ULX7 3/20 0.40
MAPT P10636 3/20 0.40
GAA P10253 2/20 0.40
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
LMNA P02545 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4939167 0.69 CYP1A2 (0.43) CYP1A2TSHRCYP2C9CYP2C19ALDH1A1
SCHEMBL15475066 0.69 CYP1A2 (0.43) CYP1A2TSHRCYP2C9CYP2C19ALDH1A1
SCHEMBL1662475 0.68 CYP1A2 (0.42) CYP1A2TSHRCYP2C9CYP2C19ALDH1A1
SCHEMBL4915482 0.68 CYP1A2 (0.42) CYP1A2TSHRCYP2C9CYP2C19ALDH1A1
SCHEMBL9626894 0.67 TSHR (0.48) CYP1A2TSHRALDH1A1CA12CA1
SCHEMBL3841776 0.65 CYP1A2 (0.43) CYP1A2TSHRCYP2C9CYP2C19ALDH1A1
SCHEMBL2650968 0.65 CYP1A2 (0.43) CYP1A2TSHRCYP2C9CYP2C19ALDH1A1
SCHEMBL2027730 0.64 ALDH1A1 (0.43) TSHRALDH1A1CA12CA1CA2
SCHEMBL1368261 0.64 KMT2A (0.42) CYP1A2TSHRALDH1A1CA12CA1
SCHEMBL11259365 0.64 CYP1A2 (0.42) CYP1A2TSHRCYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2421501-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF The Procter & Gamble Company (US) 2012-02-29 EP disclosed
US-7988740-B2 Keratin dyeing compositions comprising a radical scavenger and use thereof THE PROCTER & GAMBLE COMPANY (US) 2011-08-02 US disclosed
US-20110035885-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof NOXELL CORPORATION 2011-02-17 US disclosed
WO-2010123863-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2010-10-28 WO disclosed
EP-1493593-B1 Thermal transfer recording system having an amorphous dye phase POLAROID CORP (US) 2006-05-31 EP disclosed
EP-1493593-A1 Thermal transfer recording system having an amorphous dye phase Polaroid Corporation (US) 2005-01-05 EP disclosed
EP-1263607-B1 THERMAL TRANSFER RECORDING SYSTEM HAVING AN AMORPHOUS DYE PHASE POLAROID CORP (US) 2004-12-01 EP disclosed
US-6537410-B2 Thermal transfer recording system POLAROID CORPORATION 2003-03-25 US disclosed
EP-1263607-A1 THERMAL TRANSFER RECORDING SYSTEM HAVING AN AMORPHOUS DYE PHASE POLAROID CORPORATION (US) 2002-12-11 EP disclosed
US-6485527-B1 Use of reactive dyes for dyeing hair BASF AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed
WO-1991008265-A1 AZO COMPOUNDS AND THEIR USE AS DYES, 1-SULPHO-6-CARBOXYL-AMINO NAPHTHALINE, ITS USE AS A DIAZO COMPONENT AND PROCESS FOR THE PRODUCTION OF THESE COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-13 WO disclosed
US-5021558-A Color strength, fastness HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed
US-5003049-A Fiber-Reactive Dyes for Hydroxy Textiles BASF AKTIENGESELLSCHAFT (DE) 1991-03-26 US disclosed
EP-0183651-B1 METAL COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1990-05-23 EP disclosed
US-4873320-A COLORFASTNESS; FOR COTTON AND CELLULOSE FIBER MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-10 US disclosed
US-4847365-A POLYAMIDES, POLYESTERS, OLEFIN POLYMERS CIBA-GEIGY CORPORATION (US) 1989-07-11 US disclosed
US-4677199-A Reactive dyes containing substituted 4-fluoropyridaz-6-one radicals BASF AKTIENGESELLSCHAFT (DE) 1987-06-30 US disclosed
EP-0183651-A2 Metal complexes, process for their preparation and their use CIBA-GEIGY AG (CH) 1986-06-04 EP disclosed
US-4141899-A ANTIULCER, ANTISECRETORY SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) 1979-02-27 US disclosed
US-4123429-A 1:1 Chromiferous complex azo compounds having a bidentate chelating group and a monofunctional neutral ligand PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110035885-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof KRT18, LPO, CYB5R3 CYP1A2 1677/4885TSHR 4803/4885CYP2C9 2143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.