SCHEMBL2027730

SCHEMBL2027730

CCOC(=O)C1=CC(=O)NC1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.43
MAPT P10636 5/20 0.43
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
POLB P06746 3/20 0.43
KDM4E B2RXH2 4/20 0.42
LMNA P02545 3/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HTT P42858 1/20 0.40
GAA P10253 3/20 0.40
FHIT P49789 1/20 0.40
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA7 P43166 3/20 0.39
CA9 Q16790 3/20 0.39
CA14 Q9ULX7 3/20 0.39
HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9267958 0.84 TSHR (0.49) ALDH1A1KMT2AMEN1KDM4ELMNA
SCHEMBL12243908 0.81 KMT2A (0.39) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL12220426 0.80 ALDH1A1 (0.39) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL502220 0.79 MAPT (0.38) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL9626894 0.74 TSHR (0.48) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL8081015 0.71 SMN1; SMN2 (0.44) ALDH1A1KMT2AKDM4ELMNAL3MBTL1
SCHEMBL3172992 0.70 KMT2A (0.35) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL22468788 0.68 HSD17B3 (0.42) ALDH1A1MAPTKMT2AMEN1HTT
SCHEMBL6022461 0.67
SCHEMBL8909319 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110914240-B Norbornenone compounds releasing carbon monoxide 奥塔哥创新有限公司 2024-02-20 CN disclosed
EP-2558538-A2 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS Oligasis (US) 2013-02-20 EP disclosed
EP-2512462-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES Oligasis (US) 2012-10-24 EP disclosed
WO-2011130694-A2 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS OLIGASIS (US) 2011-10-20 WO disclosed
EP-1270642-B1 BRANCHED POLYALKYLENE GLYCOLS KYOWA HAKKO KIRIN CO LTD (JP) 2011-08-31 EP disclosed
WO-2011075736-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES OLIGASIS (US) 2011-06-23 WO disclosed
EP-1400550-B1 BRANCHED POLYALKYLENE GLYCOLS KYOWA HAKKO KIRIN CO LTD (JP) 2010-06-23 EP disclosed
US-7691367-B2 Branched polyalkylene glycols KYOWA HAKKO KIRIN CO., LTD. (JP) 2010-04-06 US disclosed
US-7547765-B2 Branched polyalkylene glycols KYOWA HAKKO KIRIN CO., LTD. (JP) 2009-06-16 US disclosed
US-20080125350-A1 BRANCHED POLYALKYLENE GLYCOLS KYOWA HAKKO KOGYO CO., LTD. (JP) 2008-05-29 US disclosed
EP-1313750-A1 METHOD FOR PRODUCING WATER-SOLUBLE SACCHARIDE CONJUGATES AND SACCHARIDE MIMETICS BY DIELS-ALDER REACTION Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2003-05-28 EP disclosed
EP-1270642-A1 BRANCHED POLYALKYLENE GLYCOLS KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-01-02 EP disclosed
WO-2002016378-A1 METHOD FOR PRODUCING WATER-SOLUBLE SACCHARIDE CONJUGATES AND SACCHARIDE MIMETICS BY DIELS-ALDER REACTION Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2002-02-28 WO disclosed
EP-0726275-B1 Benzodiazepine protein conjugates and their use in benzodiazepine immunoassays BOEHRINGER MANNHEIM GMBH (DE) 1999-01-27 EP disclosed
EP-0618192-B1 Homobidental, trifunctional maleimide linkers and their application in immunologically active conjugates BOEHRINGER MANNHEIM GMBH (DE) 1998-09-16 EP disclosed
US-5662911-A USED AS IMMUNOGENS TO OBTAIN ANTIBODIES TO BENZODIAZEPINES BOEHRINGER MANNHEIM GMBH (DE) 1997-09-02 US disclosed
US-5606030-A IMMUNOGENIC PROTEINS; USEFUL FOR INDUCING ANTI-PEPTIDE IMMUNE RESPONSES IN MAMMALS, HIV-NEUTRALIZING ANTIBODIES IN MAMMALS AND FORMULATING VACCINES TO PREVENT HIV INFECTIONS MERCK & CO., INC. (US) 1997-02-25 US disclosed
EP-0726275-A1 Benzodiazepine protein conjugates and their use in benzodiazepine immunoassays Roche Diagnostics GmbH (DE) 1996-08-14 EP disclosed
EP-0618192-A1 Homobidental, trifunctional mazeimide linkers and their application in immunologically active conjugates Roche Diagnostics GmbH (DE) 1994-10-05 EP disclosed
EP-0467700-A2 Coconjugate vaccines comprising immunogenic protein, HIV related peptides, and anionic moieties MERCK & CO. INC. (US) 1992-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080125350-A1 BRANCHED POLYALKYLENE GLYCOLS LNPEP, ANPEP, ENPEP ALDH1A1 2967/4885MAPT 4396/4885KMT2A 4612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.