Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 4/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14648748 | 0.81 | GABRA2 (0.45) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL7713033 | 0.79 | GABRB3 (0.46) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL7713040 | 0.79 | GABRB3 (0.46) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL7707263 | 0.78 | GABRB3 (0.48) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL6926985 | 0.78 | GABRP (0.57) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL7713311 | 0.76 | GABRB3 (0.41) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL6924684 | 0.76 | GABRA2 (0.42) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL7711379 | 0.74 | GABRB3 (0.43) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL6926934 | 0.74 | GABRP (0.65) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL6055657 | 0.73 | GABRB3 (0.45) | GABRA2GABRB2GABRB3GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518266-B1 | 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides | 3-DIMENSIONAL PHARMACEUTICALS | 2003-02-11 | — | — | US | claimed |
| WO-2001007413-A1 | 1-ARYL-3-THIOALKYL PYRAZOLES, THE SYNTHESIS THEREOF AND THE USE THEREOF AS INSECTICIDES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | claimed |
| US-6518266-B1 | 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides | 3-DIMENSIONAL PHARMACEUTICALS | 2003-02-11 | — | — | US | disclosed |
| WO-2001007413-A1 | 1-ARYL-3-THIOALKYL PYRAZOLES, THE SYNTHESIS THEREOF AND THE USE THEREOF AS INSECTICIDES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | disclosed |