SCHEMBL7707263

SCHEMBL7707263

N#Cc1cn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRB3 P28472 6/20 0.48
GABRA2 P47869 6/20 0.48
GABRB2 P47870 6/20 0.48
GABRP O00591 5/20 0.48
GABRD O14764 5/20 0.48
GABRA1 P14867 5/20 0.48
GABRB1 P18505 5/20 0.48
GABRG2 P18507 5/20 0.48
GABRA5 P31644 5/20 0.48
GABRA3 P34903 5/20 0.48
GABRA4 P48169 5/20 0.48
GABRE P78334 5/20 0.48
GABRA6 Q16445 5/20 0.48
GABRG1 Q8N1C3 5/20 0.48
GABRG3 Q99928 5/20 0.48
GABRQ Q9UN88 5/20 0.48
NR1I2 O75469 1/20 0.46
LMNA P02545 1/20 0.46
CYP3A4 P08684 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7713040 0.84 GABRB3 (0.46) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL7713033 0.84 GABRB3 (0.46) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL28073650 0.81 GABRB3 (0.52) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL6926985 0.80 GABRP (0.57) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL7711379 0.79 GABRB3 (0.43) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL6055657 0.78 GABRB3 (0.45) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL6923866 0.78 GABRA2 (0.42) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL6924684 0.78 GABRA2 (0.42) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL7713311 0.78 GABRB3 (0.41) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL6104867 0.78 GABRB3 (0.41) GABRB3GABRA2GABRB2GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637438-B2 Protoporphyrinogen oxidase inhibitors ENKO CHEM, INC. (US) 2026-05-26 US disclosed
US-12635649-B2 Soybean line EC2020472 SYNGENTA CROP PROTECTION AG (CH) 2026-05-26 US disclosed
US-12622398-B2 Soybean line EC2020188 SYNGENTA CROP PROTECTION AG (CH) 2026-05-12 US disclosed
US-20260117243-A1 Plants Having Increased Tolerance to Herbicides BASF AGRO BV (NL) 2026-04-30 US disclosed
US-20260101859-A1 SOYBEAN VARIETY SYNGENTA CROP PROTECTION AG (CH) 2026-04-16 US disclosed
US-12599085-B2 Soybean variety CL1945155 SYNGENTA CROP PROTECTION AG (CH) 2026-04-14 US disclosed
US-20260068883-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS ENKO CHEM, INC. (US) 2026-03-12 US disclosed
US-12570994-B2 Plants having increased tolerance to herbicides BASF Agro B.V. (NL) 2026-03-10 US disclosed
US-12529066-B2 Plants having increased tolerance to herbicides BASF Agro B.V. (NL) 2026-01-20 US disclosed
US-12520795-B2 Soybean variety SYNGENTA CROP PROTECTION AG (CH) 2026-01-13 US disclosed
US-5916618-A PESTICIDE FOR MEDICATED FEEDSTUFF, DIETARY CONCENTRATE OR SUPPLEMENT RHONE-POULENC AGRICULTURE LTD. (GB) 1999-06-29 US disclosed
US-5714191-A PESTICIDES USED IN MEDICATED FEEDSTUFF, MINERAL SALT LICK OR EDIBLE BAIT RHONE-POULENC AGRICULTURE LTD. (GB) 1998-02-03 US disclosed
US-5608077-A INSECTICIDES, NEMATOCIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS RHONE-POULENC AGRICULTURE LTD. (GB) 1997-03-04 US disclosed
US-5547974-A INSECTICIDES, NEMATOCIDES, ANTHELMINTICS RHONE-POULENC AGRICULTURE LTD. (GB) 1996-08-20 US disclosed
EP-0234119-B1 Pesticidal method using N-phenylpyrazoles RHONE POULENC AGROCHIMIE (FR) 1994-08-24 EP disclosed
EP-0579280-A1 Pesticidal method using N-phenylpyrazoles RHONE-POULENC AGROCHIMIE (FR) 1994-01-19 EP disclosed
US-5232940-A Controlling insects, plant nematodes, helminths, protozoa BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) 1993-08-03 US disclosed
EP-0234119-A1 Pesticidal method using N-phenylpyrazoles RHONE-POULENC AGROCHIMIE (FR) 1987-09-02 EP disclosed
CN-86108643-A Insecticidal method using N-phenylpyrazoles 1987-07-29 CN disclosed
WO-1987003781-A1 PESTICIDAL METHOD USING N-PHENYLPYRAZOLES MAY & BAKER LIMITED (GB) 1987-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570994-B2 Plants having increased tolerance to herbicides PPOX, MTR, DAO GABRB3 1487/4885GABRA2 3180/4885GABRB2 1409/4885
US-12599085-B2 Soybean variety CL1945155 CLK2, CLK1, CLK4 GABRB3 2424/4885GABRA2 2480/4885GABRB2 2083/4885
US-20260101859-A1 SOYBEAN VARIETY CLK2, CLK1, CLK3 GABRB3 2433/4885GABRA2 3403/4885GABRB2 2306/4885
US-12635649-B2 Soybean line EC2020472 CLK2, CLK1, CLK4 GABRB3 2827/4885GABRA2 3562/4885GABRB2 2602/4885
US-12637438-B2 Protoporphyrinogen oxidase inhibitors PPOX, CYP4X1, CBR3 GABRB3 1951/4885GABRA2 3539/4885GABRB2 2266/4885
US-12622398-B2 Soybean line EC2020188 LPCAT1, PEX14, PLTP GABRB3 3820/4885GABRA2 3215/4885GABRB2 3638/4885
US-20260068883-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS PPOX, CYC1, CBR3 GABRB3 2733/4885GABRA2 3783/4885GABRB2 2965/4885
US-12529066-B2 Plants having increased tolerance to herbicides PPOX, DAO, GLUL GABRB3 149/4885GABRA2 613/4885GABRB2 111/4885
US-20260117243-A1 Plants Having Increased Tolerance to Herbicides PPOX, PNPO, CYP4X1 GABRB3 1446/4885GABRA2 2424/4885GABRB2 1304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.