Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830931 | 0.88 | KMT2A (0.48) | ALDH1A1LMNAGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL3066507 | 0.87 | KMT2A (0.47) | ALDH1A1LMNAGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6926861 | 0.86 | KMT2A (0.46) | ALDH1A1LMNAGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6690559 | 0.85 | HTR6 (0.45) | ALDH1A1LMNAGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6925065 | 0.85 | ALDH1A1 (0.57) | ALDH1A1LMNAGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6827869 | 0.82 | ALDH1A1 (0.57) | ALDH1A1LMNAGAASMN1; SMN2HTT | |
| SCHEMBL6924661 | 0.82 | LMNA (0.57) | ALDH1A1LMNASMN1; SMN2NPC1KMT2A | |
| SCHEMBL3061795 | 0.79 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL6932063 | 0.79 | LMNA (0.44) | ALDH1A1LMNASMN1; SMN2HTTKMT2A | |
| SCHEMBL6830792 | 0.78 | ALDH1A1 (0.59) | ALDH1A1LMNAGAAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |