Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | PKLR | P30613 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054059 | 0.87 | HTR6 (0.50) | HTR6PKMPKLRALDH1A1MEN1 | |
| SCHEMBL3053691 | 0.85 | LMNA (0.54) | PKMPKLRALDH1A1KMT2ARAB9A | |
| SCHEMBL6923902 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ALMNAGAA | |
| SCHEMBL3071207 | 0.78 | L3MBTL1 (0.51) | PKMPKLRKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL3063905 | 0.75 | ALDH1A1 (0.56) | HTR6ALDH1A1MEN1KMT2APTGDR2 | |
| SCHEMBL3077251 | 0.73 | ALDH1A1 (0.57) | PKMALDH1A1RAB9ALMNAGAA | |
| SCHEMBL7789916 | 0.73 | KMT2A (0.75) | PKMPKLRALDH1A1MEN1KMT2A | |
| SCHEMBL6830931 | 0.73 | KMT2A (0.48) | ALDH1A1MEN1KMT2ALMNAGAA | |
| SCHEMBL6926084 | 0.72 | POLB (0.56) | PKMPKLRALDH1A1KMT2ARAB9A | |
| SCHEMBL13729809 | 0.72 | PKLR (0.47) | HTR6PKMPKLRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |