SCHEMBL6923995

SCHEMBL6923995

CC(OC(=O)C(N)CCC(N)=O)N(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
KMT2A Q03164 1/20 0.46
DPP4 P27487 2/20 0.41
DPP9 Q86TI2 2/20 0.41
DPP8 Q6V1X1 1/20 0.41
CHRNB2 P17787 4/20 0.40
CHRNA4 P43681 4/20 0.40
CHRNB4 P30926 2/20 0.40
CHRNA3 P32297 1/20 0.40
LTA4H P09960 1/20 0.32
GABRP O00591 2/20 0.31
GABRD O14764 2/20 0.31
GABRA1 P14867 2/20 0.31
GABRB1 P18505 2/20 0.31
GABRG2 P18507 2/20 0.31
GABRB3 P28472 2/20 0.31
GABRA5 P31644 2/20 0.31
GABRA3 P34903 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10874134 0.86 GABRP (0.47) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL7775146 0.82 ALOX15 (0.52) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL5964545 0.82 ALOX15 (0.52) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL23408879 0.77 ALOX15 (0.47) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL22772958 0.77 ALOX15 (0.57) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL10888190 0.77 ALOX15 (0.47) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL2482058 0.75 ALOX15 (0.53) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL3180147 0.74 ALOX15 (0.52) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL10192702 0.74 ALOX15 (0.56) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL716803 0.74 ALOX15 (0.56) ALOX15BLMPMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1392756-A2 LIPID-POLYMER-CONJUGATES Yamanouchi Europe B.V. (NL) 2004-03-03 EP disclosed
WO-2002098951-A2 LIPID-POLYMER-CONJUGATES YAMANOUCHI EUROPE B.V. (NL) 2002-12-12 WO disclosed