Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6642272 | 0.90 | SMO (0.43) | GAARAB9ANPC1TNFNOD1 | |
| SCHEMBL6259089 | 0.81 | GAA (0.53) | GAALRRK2SRPK3RAB9ANPC1 | |
| SCHEMBL7086871 | 0.81 | HTR2C (0.49) | GAALRRK2SRPK3RAB9AHTR2A | |
| SCHEMBL6646726 | 0.79 | PTGS1 (0.46) | GAAKDM4EALDH1A1 | |
| SCHEMBL6646519 | 0.79 | GAA (0.41) | GAARAB9ANPC1TNFNOD1 | |
| SCHEMBL7083646 | 0.78 | GAA (0.49) | GAALRRK2NTRK1SRPK3RAB9A | |
| SCHEMBL6644345 | 0.75 | SMO (0.44) | GAANTRK1RAB9ANPC1TNF | |
| SCHEMBL7172033 | 0.73 | HDAC2 (0.41) | GAALRRK2NTRK1 | |
| SCHEMBL6792746 | 0.72 | PTGS1 (0.57) | RAB9ANPC1 | |
| SCHEMBL6643633 | 0.72 | MEN1 (0.41) | RAB9AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |