Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923871 | 0.94 | L3MBTL1 (0.54) | L3MBTL1GLO1HSP90AA1NPC1RAB9A | |
| SCHEMBL6920288 | 0.92 | L3MBTL1 (0.53) | L3MBTL1GLO1HSP90AA1RAB9AATM | |
| SCHEMBL6922985 | 0.90 | L3MBTL1 (0.50) | L3MBTL1GLO1HSP90AA1GABRA1GABRB2 | |
| SCHEMBL6923317 | 0.81 | L3MBTL1 (0.42) | L3MBTL1GLO1ATM | |
| SCHEMBL1347360 | 0.80 | GLO1 (0.44) | L3MBTL1GLO1PLAT | |
| SCHEMBL6827416 | 0.77 | KMO (0.40) | L3MBTL1 | |
| SCHEMBL6827991 | 0.77 | KMO (0.50) | L3MBTL1 | |
| SCHEMBL11360635 | 0.73 | L3MBTL1 (0.67) | L3MBTL1GLO1HSP90AA1IDH1ATM | |
| SCHEMBL6827346 | 0.72 | ATM (0.42) | CHRNB2CHRNB4CHRNA3ATMGABRA1 | |
| SCHEMBL6922814 | 0.67 | L3MBTL1 (0.57) | L3MBTL1GLO1HSP90AA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | claimed |
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |