Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 6/20 | 0.39 |
| ▸ | RXRB | P28702 | 5/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | GIPR | P48546 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823842 | 0.90 | PDE4D (0.41) | PDE4APDE4BPDE4CPDE4DNR1I2 | |
| SCHEMBL6827991 | 0.86 | KMO (0.50) | KMOPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6920288 | 0.85 | L3MBTL1 (0.53) | L3MBTL1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL6826222 | 0.79 | KCNH2 (0.38) | L3MBTL1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL6924508 | 0.77 | L3MBTL1 (0.57) | L3MBTL1 | |
| SCHEMBL6923317 | 0.74 | L3MBTL1 (0.42) | L3MBTL1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL6824274 | 0.72 | BACE1 (0.43) | HRH3 | |
| SCHEMBL6827138 | 0.71 | L3MBTL1 (0.76) | RXRARXRBL3MBTL1EGFR | |
| SCHEMBL6826999 | 0.71 | L3MBTL1 (0.76) | RXRARXRBL3MBTL1EGFR | |
| SCHEMBL6919295 | 0.70 | NR1I2 (0.42) | KMONR1I2KDM4BCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | claimed |
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |