Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 3/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 12/20 | 0.46 |
| ▸ | EIF4E | P06730 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924937 | 0.83 | PRKCZ (0.53) | PRKCZANO1GRM2ALDH1A1LMNA | |
| SCHEMBL6926065 | 0.81 | MPL (0.50) | PRKCZANO1ALDH1A1HPGD | |
| SCHEMBL12465762 | 0.79 | PRKCZ (0.47) | PRKCZEIF4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL18956233 | 0.79 | PRKCZ (0.52) | PRKCZANO1KMOANO2ALDH1A1 | |
| SCHEMBL2369108 | 0.77 | PRKCZ (0.63) | PRKCZANO1ANO2ALDH1A1LMNA | |
| SCHEMBL6927702 | 0.77 | PRKCZ (0.43) | PRKCZANO1ANO2ALDH1A1LMNA | |
| SCHEMBL6927774 | 0.76 | PRKCZ (0.52) | PRKCZANO1KMOANO2ALDH1A1 | |
| SCHEMBL6925740 | 0.76 | PRKCZ (0.40) | PRKCZEIF4EKMOGRM2ALDH1A1 | |
| SCHEMBL12466203 | 0.75 | HSD17B10 (0.51) | PRKCZANO1ALDH1A1LMNAMEN1 | |
| SCHEMBL6925990 | 0.74 | PRKCZ (0.38) | PRKCZALDH1A1LMNAMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109551-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-09-09 | — | — | WO | disclosed |