Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 10/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927774 | 0.84 | PRKCZ (0.52) | PRKCZANO1ALDH1A1HPGDMEN1 | |
| SCHEMBL18956233 | 0.81 | PRKCZ (0.52) | PRKCZANO1ALDH1A1HPGDANO2 | |
| SCHEMBL6924898 | 0.77 | PRKCZ (0.47) | PRKCZANO1ALDH1A1HPGDMEN1 | |
| SCHEMBL2369108 | 0.76 | PRKCZ (0.63) | PRKCZANO1ALDH1A1HPGDMEN1 | |
| SCHEMBL2367950 | 0.76 | PRKCZ (0.63) | PRKCZANO1ALDH1A1HPGDMEN1 | |
| SCHEMBL12465762 | 0.75 | PRKCZ (0.47) | PRKCZALDH1A1HPGDMEN1LMNA | |
| SCHEMBL12466203 | 0.75 | HSD17B10 (0.51) | PRKCZANO1ALDH1A1HPGDMEN1 | |
| SCHEMBL12465745 | 0.75 | HSD17B10 (0.51) | PRKCZALDH1A1HPGDMEN1LMNA | |
| SCHEMBL6925779 | 0.74 | NPC1 (0.38) | PRKCZMAPT | |
| SCHEMBL1799330 | 0.74 | KMT2A (0.69) | PRKCZALDH1A1HPGDMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109551-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-09-09 | — | — | WO | disclosed |