Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927534 | 0.86 | PRKCZ (0.47) | PRKCZMAPTPOLBNPSR1ALDH1A1 | |
| SCHEMBL6924898 | 0.83 | PRKCZ (0.47) | PRKCZALDH1A1GRM2MEN1KMT2A | |
| SCHEMBL6926065 | 0.81 | MPL (0.50) | PRKCZNPSR1ALDH1A1HSD17B10HPGD | |
| SCHEMBL12465762 | 0.79 | PRKCZ (0.47) | PRKCZMAPTALDH1A1HSD17B10TSHR | |
| SCHEMBL6925553 | 0.78 | MAPT (0.43) | PRKCZMAPTPOLBNPSR1ALDH1A1 | |
| SCHEMBL13926187 | 0.77 | ALDH1A1 (0.70) | PRKCZMAPTPOLBALDH1A1HSD17B10 | |
| SCHEMBL14803287 | 0.74 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AANO1 | |
| SCHEMBL6925990 | 0.74 | PRKCZ (0.38) | PRKCZMAPTPOLBNPSR1ALDH1A1 | |
| SCHEMBL28760465 | 0.73 | ALDH1A1 (0.54) | PRKCZMAPTPOLBNPSR1ALDH1A1 | |
| SCHEMBL6926608 | 0.71 | MEN1 (0.64) | HSD17B10TSHRMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109551-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-09-09 | — | — | WO | disclosed |