Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 2/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.42 |
| ▸ | FEN1 | P39748 | 8/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | CDC14B | O60729 | 1/20 | 0.36 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924898 | 0.81 | PRKCZ (0.47) | PRKCZALDH1A1HPGDANO1 | |
| SCHEMBL6924937 | 0.81 | PRKCZ (0.53) | PRKCZALDH1A1HPGDHSD17B10ANO1 | |
| SCHEMBL28599809 | 0.80 | PRKCZ (0.48) | PRKCZKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12466271 | 0.78 | ADORA1 (0.49) | PRKCZKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12465762 | 0.77 | PRKCZ (0.47) | MPLPRKCZKDM4EALDH1A1HPGD | |
| SCHEMBL6926076 | 0.77 | MPL (0.51) | MPLPRKCZAPPALOX5APFEN1 | |
| SCHEMBL6925990 | 0.71 | PRKCZ (0.38) | PRKCZKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6925553 | 0.70 | MAPT (0.43) | PRKCZKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2367950 | 0.69 | PRKCZ (0.63) | PRKCZALDH1A1HPGDHSD17B10ANO1 | |
| SCHEMBL2368735 | 0.69 | GRIN2C (0.56) | PRKCZKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109551-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-09-09 | — | — | WO | disclosed |