Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | MGAM | O43451 | 3/20 | 0.47 |
| ▸ | SI | P14410 | 3/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261038 | 0.92 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3416077 | 0.86 | LTA4H (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3421079 | 0.86 | GAA (0.55) | CA12CA1CA2CA7CA9 | |
| Phenol SCHEMBL8208774 | 0.85 | LMNA (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3418564 | 0.83 | ESR1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3421205 | 0.83 | PTPN1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20391486 | 0.83 | ESR1 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6933377 | 0.83 | ALOX15 (0.48) | CA12CA1CA2CA7CA9 | |
| Hydroquinone SCHEMBL8024416 | 0.82 | ALDH1A1 (0.59) | CA12CA1CA2CA7CA9 | |
| Hydroquinone SCHEMBL7626940 | 0.82 | ALDH1A1 (0.59) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363876-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | Abbott Laboratories (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002064550-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | ABBOTT LABORATORIES (US) | 2002-08-22 | — | — | WO | disclosed |