Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838678 | 0.93 | KDM4E (0.43) | GPR119KDM4EPKMHPGDSTHRB | |
| SCHEMBL6927289 | 0.82 | GBA1 (0.40) | GPR119KDM4EPKMTHRBLMNA | |
| SCHEMBL6833883 | 0.82 | KDM4E (0.42) | GPR119KDM4EPKMHPGDSTHRB | |
| SCHEMBL6927222 | 0.81 | ACKR3 (0.45) | THRBSMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL6838661 | 0.81 | CETP (0.42) | GPR119KDM4EPKMHPGDSLMNA | |
| SCHEMBL6837673 | 0.79 | HPGDS (0.47) | GPR119KDM4EPKMHPGDSTHRB | |
| SCHEMBL6928754 | 0.79 | CKS1B (0.38) | GPR119PTGER4BRD4 | |
| SCHEMBL6929719 | 0.79 | PTGER4 (0.37) | PTGER4BRD4 | |
| SCHEMBL6927078 | 0.78 | KDM4E (0.45) | GPR119KDM4EPKM | |
| SCHEMBL6926356 | 0.76 | ALDH1A1 (0.37) | KDM4EGAASMN1; SMN2LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |