Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929719 | 0.88 | PTGER4 (0.37) | PTGER4BRD4 | |
| SCHEMBL27570136 | 0.87 | ACP1 (0.40) | PTGER4 | |
| SCHEMBL6928550 | 0.82 | PTGER4 (0.40) | PTGER4BRD4 | |
| SCHEMBL6926668 | 0.82 | IDO1 (0.40) | BRD4 | |
| SCHEMBL6838678 | 0.81 | KDM4E (0.43) | CKS1BSKP1SKP2BRD4GPR119 | |
| SCHEMBL6926356 | 0.81 | ALDH1A1 (0.37) | PTGER4BRD4 | |
| SCHEMBL6833951 | 0.80 | PTGER4 (0.38) | PTGER4BRD4 | |
| SCHEMBL6929687 | 0.79 | KDM4E (0.39) | PTGER4BRD4 | |
| Hydrochloric Acid SCHEMBL6927487 | 0.79 | KDM4E (0.35) | PTGER4 | |
| SCHEMBL6925924 | 0.79 | GPR119 (0.44) | PTGER4BRD4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |