SCHEMBL6926356

SCHEMBL6926356

CNC(=S)N1CCC(CCn2c(-c3ccccc3)nc3c(Cl)nc4ccccc4c32)CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.37
KDM4E B2RXH2 6/20 0.37
HSD17B10 Q99714 6/20 0.37
HPGD P15428 5/20 0.37
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
RAB9A P51151 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
ACP1 P24666 1/20 0.35
TLR7 Q9NYK1 2/20 0.35
KMT2A Q03164 1/20 0.34
ALOX12 P18054 2/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
IDO1 P14902 1/20 0.34
GAA P10253 1/20 0.34
PTGER4 P35408 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6927487 0.84 KDM4E (0.35) ALDH1A1KDM4EHSD17B10HPGDTSHR
SCHEMBL6928754 0.81 CKS1B (0.38) PTGER4BRD4
SCHEMBL6930500 0.81 ALDH1A1 (0.35) ALDH1A1KDM4EHSD17B10HPGDRAB9A
SCHEMBL6925914 0.80 NPY1R (0.44) ALDH1A1RAB9AACP1LMNASMN1; SMN2
SCHEMBL6929719 0.79 PTGER4 (0.37) ACP1IDO1PTGER4BRD4
Hydrochloric Acid SCHEMBL6923145 0.79 NPY1R (0.43) ACP1
SCHEMBL6928550 0.78 PTGER4 (0.40) ALDH1A1KDM4EHSD17B10HPGDTSHR
SCHEMBL6922923 0.77 NPY1R (0.41) ALDH1A1ACP1KMT2APTGER4
SCHEMBL6926668 0.75 IDO1 (0.40) ACP1TLR7KMT2AIDO1BRD4
Fumaric Acid SCHEMBL729085 0.75 HDAC1 (0.41) ALDH1A1KDM4EHSD17B10RAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518265-B1 1H-imidazopyridine derivatives HOKURIKU SEIYAKU CO., LTD. (JP) 2003-02-11 US disclosed
EP-1104764-A1 1H-IMIDAZOPYRIDINE DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2001-06-06 EP disclosed